Skip to main content
. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Anal Chem. 2009 Apr 1;81(7):2618–2625. doi: 10.1021/ac802538x

Figure 1. Immobilization chemistry used in this work.

Figure 1

(1) The porous silica particles were rinsed in 0.05% HCl (aq) then reacted with 0.5% of 3-aminopropyltriethoxysilane in ethanol for 1h, (2) followed by suspension in acetonitrile and cyanuric chloride activation in the presence of N,N-diisopropylethylamine for 2h. (3) Amino-C6-oligonucleotide probes were allowed to react with the particles overnight.