Table 2. Amblyopic eye visual acuity in children 3 to 6 years old in trial 1.
5-week exam | 10-week exam | 18-week exam | ||||
---|---|---|---|---|---|---|
Atropine only N = 26 |
Atropine + plano N = 30 |
Atropine only N = 24 |
Atropine + plano N = 29 |
Atropine only N = 24 |
Atropine + plano N = 31 |
|
Lines change from baseline, n (%) | ||||||
2 lines worse | 0 | 1 (3) | 0 | 1 (3) | 0 | 1 (3) |
1 line worse | 0 | 2 (7) | 0 | 1 (3) | 0 | 1 (3) |
0 | 3 (12) | 2 (7) | 2 (8) | 1 (3) | 2 (8) | 2 (6) |
1 line better | 4 (15) | 4 (13) | 2 (8) | 1 (3) | 2 (8) | 3 (10) |
2 lines better | 8 (31) | 8 (27) | 7 (29) | 5 (17) | 3 (13) | 1 (3) |
≥3 lines better | 11 (42) | 13 (43) | 13 (54) | 20 (69) | 17 (71) | 23 (74) |
Mean (SD) lines change | 2.5 (1.7) | 2.3 (2.0) | 3.3 (2.3) | 4.1 (2.9) | 4.5 (3.1) | 5.1 (3.7) |
Distribution of visual acuity, n (%) | ||||||
20/400 | 0 | 1 (3) | 0 | 1 (3) | 0 | 1 (3) |
20/320 | 1 (4) | 1 (3) | 0 | 1 (3) | 0 | 1 (3) |
20/250 | 2 (8) | 3 (10) | 1 (4) | 1 (3) | 1 (4) | 2 (6) |
20/200 | 4 (15) | 4 (13) | 2 (8) | 2 (7) | 0 | 0 |
20/160 | 1 (4) | 5 (17) | 3 (13) | 2 (7) | 2 (8) | 1 (3) |
20/125 | 4 (15) | 3 (10) | 4 (17) | 4 (14) | 4 (17) | 4 (13) |
20/100 | 4 (15) | 3 (10) | 2 (8) | 1 (3) | 1 (4) | 2 (6) |
20/80 | 5 (19) | 3 (10) | 4 (17) | 2 (7) | 1 (4) | 2 (6) |
20/63 | 3 (12) | 3 (10) | 2 (8) | 3 (10) | 5 (21) | 2 (6) |
20/50 | 1 (4) | 2 (7) | 1 (4) | 2 (7) | 5 (21) | 4 (13) |
20/40 | 0 | 1 (3) | 3 (13) | 7 (24) | 3 (13) | 0 |
20/32 | 1 (4) | 1 (3) | 2 (8) | 2 (7) | 1 (4) | 8 (26) |
20/25 | 0 | 0 | 0 | 0 | 0 | 1 (3) |
20/20 | 0 | 0 | 0 | 1 (3) | 1 (4) | 1 (3) |
20/16 | 0 | 0 | 0 | 0 | 0 | 2 (6) |
Mean (SD) logMAR Score | 0.75 (0.24) | 0.78 (0.28) | 0.65 (0.27) | 0.60 (0.34) | 0.54 (0.26) | 0.50 (0.38) |
Mean (SD) interocular difference (logMAR lines) | 6.0 (2.7) | 5.6 (2.9) | 5.2 (2.5) | 4.2 (3.5) | 4.3 (2.7) | 3.1 (4.1) |
Trial 1: weekend atropine compared with weekend atropine plus a plano lens for the sound eye in children 3 to 6 years of age.