Table 4. Amblyopic eye visual acuity in children 7 to <13 years old in Trial 2.
| 5-week exam | 17-week exam | |||
|---|---|---|---|---|
| Atropine N = 19 |
Patching N = 17 |
Atropine N = 20 |
Patching N = 13 |
|
| Change from baseline,* n (%) | ||||
| 1 line worse | 3 (16) | 0 | 2 (10) | 0 |
| 0 | 6 (32) | 3 (18) | 6 (30) | 2 (15) |
| 1 line better | 4 (21) | 9 (53) | 4 (20) | 4 (31) |
| 2 lines better | 1 (5) | 2 (12) | 3 (15) | 2 (15) |
| ≥3 lines better | 5 (26) | 3 (18) | 5 (25) | 5 (38) |
| Mean (SD) change | 1.2 (1.9) | 1.4 (1.3) | 1.5 (2.1) | 1.8 (1.3) |
| Distribution of visual acuity, n (%) | ||||
| 20/400 | 1 (5) | 0 | 0 | 0 |
| 20/320 | 3 (16) | 0 | 1 (5) | 0 |
| 20/250 | 1 (5) | 1 (6) | 3 (15) | 0 |
| 20/200 | 0 | 2 (12) | 3 (15) | 3 (23) |
| 20/160 | 5 (26) | 5 (29) | 3 (15) | 1 (8) |
| 20/125 | 3 (16) | 4 (24) | 2 (10) | 4 (31) |
| 20/100 | 2 (11) | 3 (18) | 2 (10) | 1 (8) |
| 20/80 | 0 | 1 (6) | 3 (15) | 4 (31) |
| 20/63 | 2 (11) | 1 (6) | 1 (5) | 0 |
| 20/50 | 2 (11) | 0 | 1 (5) | 0 |
| 20/40 | 0 | 0 | 0 | 0 |
| 20/32 | 0 | 0 | 0 | 0 |
| 20/25 | 0 | 0 | 1 (5) | 0 |
| Mean (SD) logMAR | 0.83 (0.27) | 0.80 (0.15) | 0.80 (0.28) | 0.78 (0.16) |
| Snellen Equivalent | 20/125-1 | 20/125 | 20/125 | 20/125+1 |
| Mean interocular difference (logMAR lines) | 8.0 (3.6) | 8.5 (1.7) | 7.6 (3.0) | 8.3 (1.8) |
*
Change from baseline in logMAR rounded to nearest line for presentation.
Trial 2: weekend atropine compared with patching 2 hours per day to the sound eye for children 7 to 12 years of age.