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. 2009 Jun;133(6):571–581. doi: 10.1085/jgp.200910206

TABLE II.

Summary of the values of maximal active force, pCa50 and nH before and after PKA treatment in PLV after reconstitution with cTn or PCRF or treatment with PP1

Maximal force (mN/mm2) pCa50 nH
Fig. 2 C
Control PLV 55.99 ± 5.92 5.55 ± 0.01 4.23 ± 0.25
cTn 52.52 ± 5.48 5.62 ± 0.01a 4.15 ± 0.35
cTn+PKA 51.17 ± 5.42 5.46 ± 0.01ab 4.56 ± 0.30
Fig. 2 D
Control PLV 53.85 ± 6.03 5.55 ± 0.02 4.16 ± 0.16
PCRF 51.42 ± 5.35 5.64 ± 0.03a 3.69 ± 0.16
PCRF + PKA 49.86 ± 5.32 5.46 ± 0.01ab 3.92 ± 0.18
Fig. 3 B
Control PLV 59.32 ± 4.51 5.55 ± 0.01 4.12 ± 0.16
PP1 56.47 ± 5.70 5.64 ± 0.02a 4.24 ± 0.35
PP1 + PKA 54.10 ± 5.66 5.46 ± 0.01ab 4.05 ± 0.20

Maximal force was obtained by activating muscle at pCa 4.5 before plotting of the force-pCa curve at each condition.

a

P < 0.05 compared with the corresponding values for control PLV (before thin filament reconstitution or PP1 treatment).

b

P < 0.05 compared with the corresponding values for thin filament reconstitution or PP1 treatment (before PKA treatment).