Table 1.
Immunization regimen
| weeks post immunization | |||||
| monkeys | 0 | 4 | 8 | 12 | |
| group 1 | 12127 | SCIV [VSV-G] | SCIV [VSV-G] | Ad5-SIV | Ad5-SIV |
| 12128 | tonsillar | tonsillar | tonsillar | tonsillar | |
| 12131 | 1.8 × 109, a | 1.2 × 108, a | 1 × 1011, b | 1 × 1011, b | |
| 12137 | |||||
| group 2 | 12133 | SCIV [VSV-G] | Ad5-SIV | ||
| 12136 | intravenous | intramuscular | |||
| 12142 | 2 × 109, a | 6 × 1011, b | |||
| 12143 | |||||
| group 3 | 12132 | SCIV [VSV-G] | SCIV [MLV] | ||
| 12138 | intravenous | intravenous | |||
| 12139 | 2 × 109, a | 3 × 107, a | |||
| 12140 | |||||
| group 4a | 12129 | Ad5GFP tonsillar | Ad5GFP tonsillar | ||
| 12130 | 1 × 1011, c | 2 × 1011, c | |||
| group 4b | 12134 | Ad5GFP intramuscular | |||
| 12141 | 6 × 1011, c | ||||
ainfectious units/ml
bnumber of particles per construct
cnumber of particles