. 2009 Jul 7;10:301. doi: 10.1186/1471-2164-10-301

Table 2.

Number of genes over-expressed in xenografts excised from GLV-1h68 infected animals

Experimental group	Days after VACV inj.
VACGLa 520445F, Affymetrix platform		VACV only	Permutation	House keeping (human/mouse)	Permutation


(cut off p²-value < 0.005 (unpaired Student t test)		(∑ 219)	test p-value	(∑ 337)	test p-value

GI-101A	7	0	N.S.	3	N.S.

GI-101A	21	219	< 0.001	(232)	< 0.001

GI-101A	42	216	< 0.001	(237)	< 0.001

HT-29	21	0	N.S.	(3)	N.S.

HT-29	42	0	N.S.	(10)	N.S.



37 K whole genome HUMAN array		All genes	Permutation

(cut off p²-value < 0.001 (unpaired Student t test)		(∑ 37 K)	test p-value


GI-101A	21	136	< 0.05

GI-101A	42	91	< 0.05

HT-29	21	4	N.S.

HT-29	42	10	N.S.



37 K whole genome Mouse array		All genes	Permutation

(cut off p²-value < 0.001 (unpaired Student t test)		(∑ 37 K)	test p-value

GI-101A	21	105	< 0.05

GI-101A	42	1026	< 0.001

HT-29	21	7	N.S.

HT-29	42	14	N.S.

* In parenthesis, genes down-regulated in GLV-1h68-infected animals referring to human/mouse house-keeping genes in the VACV chip