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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: J Immunol. 2009 Jun 1;182(11):7119–7130. doi: 10.4049/jimmunol.0802656

Figure 12. IL-17 potentiates TNF-α-induced chemokine expression in macrophages.

Figure 12

Primary microglia or macrophages isolated from C57BL/6 wild type mice were treated with the indicated concentrations of IL-17 or TNF-α or in combination for 24 h, whereupon CXCL2 and CCL2 production was quantitated by ELISA. Significant differences between unstimulated versus cytokine-treated cells are indicated by asterisks (**, p < 0.001), whereas significant differences between cells exposed to TNF-α versus TNF-α IL-17 are denoted by hatched signs (##, p < 0.001).

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