Table 2.
Results of univariable logistic regression analyses to predict attrition and weight loss success.
| Variable | Attrition | Weight Loss | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P | OR | 95% CI | P | |
| Treatment Group (Sibutramine alone) | 0.94 | 0.01 | ||||
| Sibutramine + brief lifestyle | 1.02 | 0.39 – 2.70 | 1.89 | 0.88 – 4.05 | ||
| Sibutramine + lifestyle | 1.01 | 0.39 – 2.61 | 3.78 | 1.74 – 8.18 | ||
| Lifestyle alone | 0.77 | 0.28 – 2.12 | 1.81 | 0.85 – 3.89 | ||
| Sex (Male) | 0.45 | 0.32 | ||||
| Female | 1.44 | 0.56 – 3.69 | 1.41 | 0.72 – 2.73 | ||
| Age* | 0.95 | 0.92 – 0.99 | 0.007 | 1.01 | 0.99 – 1.04 | 0.41 |
| Ethnicity (Caucasian) | 0.35 | 0.003 | ||||
| Other | 1.40 | 0.69 – 2.85 | 0.42 | 0.24 – 0.74 | ||
| Education (≤ 12 years) | 0.05 | 0.87 | ||||
| 13 – 15 years | 0.36 | 0.14 – 0.96 | 1.08 | 0.49 – 2.38 | ||
| 16 years | 0.26 | 0.09 – 0.79 | 1.38 | 0.61 – 3.14 | ||
| ≥ 17 years | 0.75 | 0.29 – 1.95 | 1.14 | 0.49 – 2.68 | ||
| Marital Status (Married) | 0.39 | 0.24 | ||||
| Other | 1.36 | 0.68 – 2.71 | 0.72 | 0.42 – 1.24 | ||
| Distance from clinic* | 0.98 | 0.95 – 1.02 | 0.34 | 1.03 | 1.003 – 1.05 | 0.03 |
| Travel time to clinic* | 0.99 | 0.96 – 1.01 | 0.34 | 1.02 | 1.00 – 1.04 | 0.06 |
| Baseline weight* | 1.01 | 0.99 – 1.03 | 0.18 | 0.99 | 0.98 – 1.01 | 0.23 |
| Baseline BMI* | 1.05 | 0.97 – 1.14 | 0.22 | 1.00 | 0.94 – 1.06 | 0.89 |
| Long weight loss attempts, past year* | 0.98 | 0.88 – 1.09 | 0.70 | 1.01 | 0.94 – 1.08 | 0.86 |
| Short weight loss attempts, past year* | 0.96 | 0.91 – 1.02 | 0.18 | 1.00 | 1.00 – 1.01 | 0.53 |
| Years since onset of overweight* | 0.95 | 0.92 – 0.99 | 0.005 | 1.03 | 1.01 – 1.05 | 0.01 |
| Number of previous 10 lb losses* | 0.90 | 0.76 – 1.07 | 0.23 | 1.05 | 0.94 – 1.19 | 0.39 |
| Weight change in previous 6 months(Stable or lost) | 0.42 | 0.64 | ||||
| Increased 5 – 10 lb | 1.12 | 0.48 – 2.65 | 0.74 | 0.39 – 1.39 | ||
| Gained > 10 lb | 1.70 | 0.75 – 3.88 | 0.89 | 0.47 – 1.70 | ||
| Weight loss goal (% initial weight)* | 13.17 | 0.22 – 807.16 | 0.22 | 0.48 | 0.02 – 11.57 | 0.65 |
| BDI-II score* | 1.07 | 1.01 – 1.12 | 0.02 | 0.96 | 0.92 – 1.00 | 0.06 |
| History of significant emotional distress (No) | 0.27 | 0.79 | ||||
| Yes | 0.63 | 0.27 – 1.45 | 0.93 | 0.51 – 1.67 | ||
| Past or present mental health treatment (No) | 0.40 | 0.83 | ||||
| Yes | 0.70 | 0.30 – 1.62 | 1.07 | 0.59 – 1.94 | ||
| Stress in past 6 months (Average or less) | 0.43 | 0.18 | ||||
| More than usual | 0.85 | 0.38 – 1.93 | 0.94 | 0.52 – 1.70 | ||
| Much more than usual | 1.58 | 0.66 – 3.78 | 0.51 | 0.24 – 1.06 | ||
| Anticipated stress in next 6 months (Average or less) | 0.27 | 0.97 | ||||
| More than usual | 0.40 | 0.13 – 1.21 | 1.06 | 0.55 – 2.06 | ||
| Much more than usual | 0.92 | 0.19 – 4.45 | 1.12 | 0.33 – 3.80 | ||
| General feelings about self (Positive) | 0.02 | 0.33 | ||||
| Mixed | 1.75 | 0.75 – 4.10 | 0.86 | 0.47 – 1.57 | ||
| Negative | 3.35 | 1.41 – 8.00 | 0.59 | 0.29 – 1.18 | ||
| Binge eating behavior (None) | 0.29 | 0.33 | ||||
| Objective overeating episodes | 0.90 | 0.32 – 2.50 | 1.73 | 0.84 – 3.57 | ||
| Subjective binge episodes | 1.13 | 0.28 – 4.55 | 0.97 | 0.34 – 2.74 | ||
| Objective binge episodes | 1.95 | 0.85 – 4.50 | 1.62 | 0.84 – 3.13 | ||
| Number of alcoholic drinks per week* | 0.94 | 0.82 – 1.08 | 0.35 | 1.01 | 0.92 – 1.10 | 0.86 |
| Tobacco use (Never smoker) | 0.72 | 0.80 | ||||
| Former smoker | 0.84 | 0.41 – 1.75 | 0.88 | 0.51 – 1.53 | ||
| Current smoker | 1.45 | 0.36 – 5.94 | 1.25 | 0.37 – 4.25 | ||
| Attendance in first 3 weeks (% of scheduled visits)* | 0.10 | 0.01 – 0.69 | 0.02 | 4.13 | 0.67 – 25.65 | 0.13 |
| Food records at week 3 (days completed)* | 0.95 | 0.89 – 1.02 | 0.18 | 1.07 | 1.02 – 1.14 | 0.01 |
| Weight loss at week 3 (% of baseline weight)* | 0.81 | 0.64 – 1.03 | 0.09 | 1.89 | 1.51 – 2.37 | <0.001 |
OR = Odds ratio, CI = Confidence interval. For categorical variables, reference groups are listed in parentheses. Continuous variables are marked with *, and odds ratios refer to one unit increases.