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Risk of thyroid cancer among 5-year acute lymphoblastic leukemia survivors without prior relapse, hematopoietic cell transplant, thyroidectomy, or other secondary malignancies.
| Observed | Expected* | SIR | 95% CI | |
|---|---|---|---|---|
| All survivors | 13 | 2.7 | 4.8 | (2.6, 8.2) |
| Chemotherapy only | 0 | 0.7 | 0 | (0, 5.1) |
| Cranial radiotherapy only | 3 | 1.7 | 1.8 | (0.4, 5.3) |
| Craniospinal radiotherapy | 10 | 0.3 | 30.3 | (14.5, 55.7) |
SIR, standardized incidence ratio;
based on age and sex-specific SEER incidence data.
