Skip to main content
. Author manuscript; available in PMC: 2010 Jun 2.
Published in final edited form as: Biochemistry. 2009 Jun 2;48(21):4476–4487. doi: 10.1021/bi8023509

Figure 8.

Figure 8

A. Left: View of the catalytically important arginine-52 (R52, green stick, N = blue, O = red) residue of MtmOIV above the flavin ring of FAD (gray stick, N = blue, O = red, P = orange). The measured distance (dotted line) between the N-atoms of the guanidine residue of R52 and the flavin ring surface is ∼ 6.2 Å in the shown conformation. The remainder of the enzyme (ribbon) is depicted in green.

B. Below: Suggested Baeyer-Villiger reaction mechanism of the MtmOIV reaction, involving the peroxyflavin and Criegee intermediates. R = deoxysugar chains