a) Longitudinal measurements in infants with at least 3 measurements (solid lines). One infant had acceptable data from all 5 stages, 7 infants had acceptable data from 4 stages, and 10 from 3 stages. There is individual variability in the change in α with age, but there is an overall increase in α of 0.012 per week of age (95%CI 0.005 to 0.019, p = 0.001) (dotted line). b) A box plot of α in all included infants grouped by age at 4, 8, 12, 16, and 20 weeks. The boundary of the box closest to zero indicates the 25th percentile, the line within the box marks the median, the black dots are the outliers, and the boundary of the box farthest from zero indicates the 75th percentile. Error bars above and below the box indicate the 90th and 10th percentiles.