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. Author manuscript; available in PMC: 2010 Jan 29.
Published in final edited form as: Neuron. 2009 Jan 29;61(2):287–300. doi: 10.1016/j.neuron.2008.12.013

Figure 6. Activation of mGluR1 and mAChR are sufficient to induce an enhancement of burst firing.

Figure 6

Layout is as described for Fig. 2. The blue bar indicates the time during which the group I mGluR agonist (DHPG, 2 μM) and mAChR agonist (carbachol, 2 μM) were washed into and out of the bath.

A. Representative (left) and group (right; n=6) data from experiments in which bath application of agonists (DHPG + carbachol) was used as the induction stimulus. B. Representative (left) and group (right; n=6) data from experiments in which bath application of agonists (DHPG + carbachol) in the presence of the mGluR5 antagonist (MPEP, 10 μM) was used as the induction stimulus. Note that MPEP was present before, during, and after wash in and wash out of agonists.