Table 3.
INVEST-GENES | Verapamil monotherapy |
Stable background therapy |
White | Hispanic | Black | Other | |
---|---|---|---|---|---|---|---|
Glu65Glu | 1412 (77%) | 121 (75%) | 454 (75%) | 743 (81%) | 466 (73%) | 153 (76%) | 50 (79%) |
Glu65Lys | 392 (22%) | 40 (24%) | 143 (24%) | 165 (18%) | 169 (26%) | 45 (23%) | 13 (21%) |
Lys65Lys | 20 (1%) | 2 (1%) | 4 (1%) | 9 (1%) | 9 (1%) | 2 (1%) | 0 |
Lys65 allele frequency | 0.12 | 0.135 | 0.13 | 0.10 | 0.14 | 0.13 | 0.10 |
Val110Val | 4591 (84%) | 128 (79%) | 493 (82%) | 1782 (86%) | 2143 (83%) | 480 (82%) | 186 (83%) |
Val110Leu | 843 (15%) | 32 (20%) | 103 (17%) | 273 (13%) | 432 (17%) | 103 (18%) | 35 (16%) |
Leu110Leu | 52 (1%) | 2 (1%) | 2 ( < 1%) | 21 (1%) | 23 (1%) | 5 (1%) | 3 (1%) |
Leu110 allele frequency | 0.09 | 0.105 | 0.09 | 0.08 | 0.09 | 0.10 | 0.09 |