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. Author manuscript; available in PMC: 2009 Jul 21.
Published in final edited form as: Pharmacogenet Genomics. 2007 Sep;17(9):719–729. doi: 10.1097/FPC.0b013e32810f2e3c

Table 3.

KCNMB1 genotype frequency by race/ethnicity and in INVEST-GENES

INVEST-GENES Verapamil
monotherapy
Stable background
therapy
White Hispanic Black Other
Glu65Glu 1412 (77%) 121 (75%) 454 (75%) 743 (81%) 466 (73%) 153 (76%) 50 (79%)
Glu65Lys 392 (22%) 40 (24%) 143 (24%) 165 (18%) 169 (26%) 45 (23%) 13 (21%)
Lys65Lys 20 (1%) 2 (1%) 4 (1%) 9 (1%) 9 (1%) 2 (1%) 0
Lys65 allele frequency 0.12 0.135 0.13 0.10 0.14 0.13 0.10
Val110Val 4591 (84%) 128 (79%) 493 (82%) 1782 (86%) 2143 (83%) 480 (82%) 186 (83%)
Val110Leu 843 (15%) 32 (20%) 103 (17%) 273 (13%) 432 (17%) 103 (18%) 35 (16%)
Leu110Leu 52 (1%) 2 (1%) 2 ( < 1%) 21 (1%) 23 (1%) 5 (1%) 3 (1%)
Leu110 allele frequency 0.09 0.105 0.09 0.08 0.09 0.10 0.09