Table 3.
Serum Levels of vWf, VEGF, Angiogenin, Fas-L, and sFas and Numbers of CECs and CPCs in Different Prognostic Groups According to the NPI.
| Variable | Healthy Controls (n = 63) | Breast Cancer NPI Groups (n = 160) | P* | ||
| GPG (n = 58) | MPG (n = 59) | PPG (n = 35) | |||
| vWf (IU/dl) | 116 (108–130) | 130 (120–145) | 123 (107–136) | 140 (124–157) | <.0001† |
| VEGF (pg/ml) | 20 (3–1600) | 135 (10–2175) | 250 (10–2900) | 30 (2–800) | .26 |
| Angiogenin (pg/ml) | 243 (163–326) | 338 (280–420) | 320 (270–390) | 345 (278–475) | <.0001‡ |
| sFas-L (pg/ml) | 182 (114–1128) | 153 (100–433) | 146 (80–338) | 154 (84–435) | .26 |
| sFas (pg/ml) | 1635 (1023–2643) | 1600 (1260–2500) | 1410 (1120–2170) | 1600 (960–2250) | .70 |
| CECs (cells/ml) | 7.7 (6–10) | 8.0 (4–8) | 8.0 (4–12) | 14.0 (8–22) | <.0001§ |
| CPCs (cells/ml) | 169 (106–241) | 113 (73–190) | 132 (96–204) | 120 (72–150) | .004¶ |
Data are median with IQRs in parentheses.
*
Kruskal-Wallis P value over the four groups. Subgroup analysis was by Dunn test.
†
HC versus GPG, P < .001; PPG, P < .001; MPG versus PPG, P < .01.
‡
HC versus GPG, MPG, and PPG, all P < .001.
§
HC versus PPG, P < .001; GPG versus PPG, P < .001; MPG versus PPG, P < .05.
¶
HC versus GPG, P < .05; HC versus PPG, P < .01.