Table 2.
Metabolic control
| Patients with suboptimal PGF (n = 5) |
Patients with optimal PGF (n = 9) |
|||||
|---|---|---|---|---|---|---|
| Inclusion | 2 years | Last follow-up | Inclusion | 2 years | Last follow-up | |
| Insulin independence | 0 (0) | 1 (20) | 1 (20) | 0 (0) | 8 (89)*† | 7 (78)*† |
| A1C (%) | 8.7 (8.0–9.2) | 7.8 (7.4–8.7) | 8.3 (7.4–9.4) | 8.3 (7.3–8.6) | 5.8 (5.4–6.5)*† | 6.2 (5.6–6.7)*† |
| Mean glucose (mmol/l) | 9.4 (7.5–12.4) | 8.7 (6.3–10.6) | 7.4 (6.3–10.6) | 8.1 (6.5–11.6) | 5.7 (5.4–6.1)*† | 5.3 (5.1–5.6)*† |
| Glucose SD (mmol/l) | 3.9 (3.0–4.9) | 1.8 (1.4–4.4) | 2.3 (1.6–4.4) | 3.1 (2.2–4.4) | 0.8 (0.7–1.0)* | 1.0 (0.6–1.4)*† |
| Low glucose excursion (%) | 9 (1–18) | 0 (0–4) | 3 (0–5) | 16 (3–22) | 0 (0–1)* | 0 (–0)* |
| Basal C-peptide (nmol/l) | 0 (–0) | 0.17 (0–0.53) | 0 (0–0.43) | 0 (–0) | 0.5 (0.4–0.6)* | 0.5 (0.43–0.6)*† |
| β-Score (0–8) | 0 (–0) | 1 (0–3.8) | 2 (0–4.5) | 0 (0) | 7 (4.8–8)*† | 7 (5.8–8)*† |
| Functioning graft | 0 (0) | 2 (40) | 2 (40) | 0 (0) | 9 (100)*† | 9 (100)*† |
| ADA criteria‡ | ||||||
| Normal | 0 (0) | 1 (20) | 0 (0) | 0 (0) | 5 (56)* | 5 (56)*† |
| Glucose intolerance | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 2 (22) | 4 (44) |
| Diabetes | 5 (100) | 4 (80) | 5 (100) | 9 (100) | 2 (22) | 0 (0) |
Data are median (interquartile range) or n (%).
*P < 0.05 versus inclusion (Wilcoxon's test);
†P < 0.05 versus suboptimal PGF (Mann-Whitney U test).
‡Defined by the American Diabetes Association (ref. 9); normal when fasting blood glucose was <5.6 mmol/l and 2-h postload glucose during OGTT was <7.8 mmol/l; diabetes when fasting blood glucose was ≥7 mmol/l or 2-h postload glucose during OGTT was ≥11.1 mmol/l; and glucose intolerance when intermediate values.