Table 4.
Comparison of persons who would be excluded for low mGFR among otherwise healthy kidney donors as determined by different classification systems
| What actually happened |
What could have happened instead | ||||
|---|---|---|---|---|---|
| Characteristics | Excluded by committee |
mGFR <80 ml/min per 1.73m2a |
eGFR <80 ml/min per 1.73m2a |
Mayo Clinic age-specific mGFR 5th percentile22 |
Cleveland Clinic age–sex-specific mGFR 5th percenile |
| n (%) | 43 (4.1) | 67 (6.3) | 148 (27.1) | 67 (6.3) | 45 (4.2)b |
| Kappa (agreement) | Reference | 0.73 | 0.16 | 0.44 | 0.41 |
| mGFR, mean±s.d., n | 73.4±4.9, 43 | 73.2±4.6, 67 | 94.1±15.4, 148 | 76.1±7.3, 67 | 75.4±6.5, 45 |
| eGFR, mean±s.d., n | 71.4±10.5, 28 | 72.5±11.4, 38 | 71.9±6.6, 148 | 77.4±15.6, 35 | 77.4±12.2, 20 |
| Age (years), mean±s.d., n | 51.6±10.4, 43 | 49±11, 67 | 46.1±9.1, 148 | 40.2±11.6, 67 | 38.7±9.6, 45 |
| Men (%) | 37.2 | 43.3 | 28.4 | 47.7 | 33.0 |
| African Americans (%) | 9 | 5.9 | 4.05 | 10.4 | 8.9 |
a
For mGFR, all living kidney donors (n=1057); for MDRD, all living kidney donors from 1996 to 2005 with measured serum creatinine (n=545).
b
Note: For the Cleveland Clinic cutoff points we are using Table 3, which splits individuals out only by age and sex.