Table 2.

Adjusted incidence rate-ratios for sudden cardiac death according to antipsychotic current use status^* and frequently prescribed individual drugs.

	Person-years	Sudden Deaths	IRR	95% CI	p-value
Nonuser	624,591	895	1	Reference
Former user	189,981	311	1.13	0.98–1.30	.0822
Current, typical**	86,735	255	2.00	1.69–2.35	<.0001
Haloperidol	21,728	58	1.61	1.16–2.24	0.0049
Thioridazine	15,715	65	3.19	2.41–4.21	<.0001
Current, atypical**	79,589	223	2.27	1.89–2.73	<.0001
Clozapine	4,654	19	3.67	1.94–6.94	<.0001
Olanzapine	27,257	75	2.04	1.52–2.74	<.0001
Quetiapine	17,355	40	1.88	1.30–2.71	0.0008
Risperidone	24,589	85	2.91	2.26–3.76	<.0001

^*Excludes 45,381 person-years and134 deaths for indeterminate users of antipsychotics as well as15,883 person-years and 52 deaths for concurrent users of multiple antipsychotics.

^**Adjusted for dose, see Appendix 1.