Table 1. Sample characteristics.
| Population | Families | n | Family size (range) | Generations (range) | Genotyped (%) | Male (%) | Female (%) | Founders (%) | Mean age (range) | Number myopic (%) | MSE (SD) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Old Order Amish (OOA) |
53 |
402 |
7.58
(3-25) |
2.09
(2-4) |
328
(82) |
182
(45) |
220
(55) |
124
(31) |
36.7
(9-85) |
184
(54.2) |
-1.61
(2.72) |
| Ashkenazi Jewish (ASHK) |
68 |
596 |
8.76
(4-17) |
2.46
(2-4) |
527
(88) |
308
(52) |
288
(48) |
181
(30) |
40.3
(9-94) |
414
(76.3) |
-3.56
(3.31) |
| Combined: | 121 | 998 | 8.25 (3-25) | 2.30 (2-4) | 855 (86) | 490 (49) | 508 (51) | 305 (31) | 38.8 (9-94) | 598 (68.4) | -2.75 (3.23) |
Myopia is defined as a manifest (or cycloplegic) refraction ≤-1 D in all four principal meridians. The proportion of myopic individuals (%) estimate excluded unknown phenotypes from the denominator. MSE=Mean Spherical Equivalent refractive error.