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. 2009 Jul 27;4(7):e6349. doi: 10.1371/journal.pone.0006349

Figure 1. Small regulatory RNA in the bovine genome.

Figure 1

Each panel shows UCSC genome browser screens. Small RNA sequence tags originating from the three small RNA libraries are shown as follows: mock-infected control - green, MOI 0.75 library - dark orange, MOI 7.5 library–magenta. Predicted pre-miRNA hairpin-like precursors are shown in blue. Arrowheads indicate alignment of sequences relative to the genomic strands. (A) Evolutionary conserved mirtron bta-mir-877 (deep red) located within intron of the ABCF1 gene. ABCF1 exon-intron junction is shown as black block (exon) and thin black line (intron) (B) New tailed mirtron located within intron of the TPRG1L gene. TPRG1L exon-intron junction is shown as light blue block (exon) and thin light blue line (intron) (C) New bovine miRNA with predicted miRNA precursors (blue) on both genomic strands and small RNAs originating from positive (right) and negative (left) genomic strands. (D) Small RNA sequence tags originating from an orphan snoRNA HBII-85 locus (blue). The distribution of small RNA tags closely resembles pattern characteristic of Dicer-dependent processing.