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. Author manuscript; available in PMC: 2009 Jul 22.
Published in final edited form as: Am J Med Genet A. 2008 Aug 1;146A(15):1917–1924. doi: 10.1002/ajmg.a.32269

Fig. 4.

Fig. 4

Sonographic images of osteogenesis imperfecta type 2 (OI type 2) showing abnormal findings. A: Absent mineralization of the calvarium (18 weeks gestation). B: Diminished mineralization of the calvarium (16 weeks gestation); arrow points to an area of calvarium mineralization. C: Femur (18 weeks gestation) showing bright areas (echodense) representing fracture and callus formation (arrow). D: Femur (16 weeks gestation) showing irregular bending (arrow). E: Saggital chest view in OI type 2 showing wavy or S-shaped ribs (arrow) and ribs that do not surround two-thirds of the chest circumference.