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Yield of UL34 mutants in different cell lines
| Virus | RSC | Vero | HEp-2 | 143TK− |
|---|---|---|---|---|
| ΔUL34 | 5.2 × 105 | 4.8 × 104 | 5.1 × 104 | 4.5 × 104 |
| UL34D(245–275) | 4.0 × 107 | 6.2 × 107 | 3.5 × 107 | 2.6 × 107 |
| UL34 repair | 5.6 × 108 | 8.6 × 108 | 4.0 × 108 | ND |
| HSV-1(F) | 6.0 × 108 | 8.2 × 108 | 5.6 × 108 | ND |
Calculated as total pfu of viruses recovered from the infected cell culture. Titration of the progeny viruses was done on rabbit skin cells (RSC). ND, not done.
