Table 3. Effect of efflux pump inhibitors and membrane permeabilizers.
Bacteria | Actinonin | AB47 | ||||
E. coli | 0 | PMBNa | PAβN | 0 | PMBNa | PAβN |
AG100 | 128 | 2 | 32 | 512 | 8 | 128 |
AG102 | 128 | 16 | 64 | 512 | 32 | 128 |
AG100A | 1 | 0.125 | 0.5 | 64 | 16 | 16 |
AG100Atet | 512 | 8 | 32 | 256 | 16 | 128 |
P. aeruginosa | ||||||
124 | 128 | 16 | 32 | >128 | 8 | 128 |
Values are means of four independent assays.
PMBN was used at 1/5 MIC.
PAβN was used at 20 µg/ml.