Table 3.
Compilation of the genes and mutants of the reductive pathway of pyrimidine degradation in Arabidopsis thaliana, including a summary of the mutant phenotypes
| Enzyme | Abbreviation | Gene | EC number | Accession | Mutant | Uracil accumulation | CO2 release (% control) | Growth on uracil as sole nitrogen source |
|---|---|---|---|---|---|---|---|---|
| Dihydropyrimidine dehydrogenase | DHPDH | PYD1 | EC 1.3.1.2 | At3g17810 | SALK_083897 (pyd1-2) | + | 60% | + |
| GABI_251F09 (pyd1-1) | + | nd | + | |||||
| Dihydropyrimidinase | DHPase | PYD2 | EC 3.5.2.2 | At5g12200 | SALK_038919 (pyd2-1) | + | 11% | – |
| GABI_114F11 (pyd2-2) | + | nd | – | |||||
| β-ureidopropionase | β-UPase | PYD3 | EC 3.5.1.6 | At5g64370 | SALK_016594 (pyd3) | + | 9% | – |
nd, not determined.