Table 1.
Biophysical properties of ERG channels in MNTB
| Voltage dependence | ||||||
|---|---|---|---|---|---|---|
| V0.5 (mV) | s.e.m. | Slope | s.e.m. | n | ||
| P12 Activation | −58.37 | 0.91 | 3.48 | 0.91 | 4 | |
| P12 Inactivation | −76.12 | 3.58 | 17.70 | 4.26 | 4 | |
| P25 Activation | −56.50 | 2.08 | 8.61* | 1.98 | 4 | |
| P25 Inactivation | −70.77 | 2.77 | 14.71 | 2.87 | 3 | |
| Deactivation kinetics | ||||||
| P12 |
P25 |
|||||
| Voltage (mV) | τfast (ms) | s.e.m. | n | τfast (ms) | s.e.m. | n |
| −130 | 15.23 | 2.62 | 4 | 21.05 | 3.83 | 3 |
| −110 | 33.15 | 3.84 | 4 | 46.78 | 5.77 | 3 |
| −90 | 99.60 | 9.06 | 4 | 162.13** | 2.11 | 3 |
Values are means ±s.e.m.n= number of cells. Statistical comparison of P12 and P25 data was performed using Student's t-test on voltage dependence (*P < 0.05) and two way ANOVA for deactivation kinetics (**P < 0.01).