Figure 4. Suppression of the myogenic response by ROK inhibition.

Effect of Y27632 (A–C; n= 5) and H1152 (D–F; n= 5) on RCA myogenic response. Representative pressure-induced changes in arterial diameter (A and D) and mean diameter (±s.e.m.)–pressure relations (B and E) for 10–120 mmHg in normal Krebs saline (Control), 1 μmol l⁻¹ Y27632 or 0.3 μmol l⁻¹ H1152, and zero [Ca²⁺]_o solution, as well as mean active constriction–pressure relations ± Y27632 (C) or ± H1152 (F). *Significantly different (P < 0.05) from control value.