Table 1.
Jugular venous noradrenaline spillover in healthy subjects at rest
| Plasma NA |
Transcranial trititiated NA plasma extraction | Plasma Flow (ml min−1) | NA spillover rate (ng min−1) | ||
|---|---|---|---|---|---|
| Art NA (pg ml−1) | JV NA (pg ml−1) | ||||
| RJV (47) | 230.5 ± 14.3 | 251.7 ± 16.8 | 0.15 ± 0.03 | 233.2 ± 14.6 | 12.1 ± 2.3†* |
| LJV (26) | 246.0 ± 14.9 | 265.3 ± 15.1 | 0.15 ± 0.02 | 220.5 ± 15.5 | 13.2 ± 2.9†* |
The mean noradrenaline (NA) spillover for brain utilising both left and right internal jugular venous (JV) samples was 12.5 ± 1.8 ng min−1.
Noradrenaline spillover for brain using combined left and right JV samples is approximately double the mean unilateral spillover measures, i.e. approximately 25 ng min−1.