Table 1.
Baseline characteristics according to quartiles of systemic myeloperoxidase (MPO)
| Characteristics | MPC Quartiles (pmol/L) |
||||
|---|---|---|---|---|---|
| <170 (n = 950) | 170–261 (n = 938) | 262–432 (n = 949) | >432 (n = 896) | p Value (trend) | |
| Age (yrs) | 75 ± 5 | 75 ± 5 | 75 ± 5 | 74 ± 5 | 0.068 |
| Men | 364 (38%) | 342 (37%) | 350 (37%) | 387 (43%) | 0.041 |
| African Americans | 142 (15%) | 149 (16%) | 167 (17%) | 166 (19%) | 0.023 |
| Systolic blood pressure (mm Hg) | 138 (21) | 136 (22) | 137 (21) | 134 (20) | 0.001 |
| Diastolic blood pressure (mm Hg) | 71 (12) | 72 (11) | 72 (10) | 71 (11) | 0.742 |
| Antihypertensive therapy | 421 (44%) | 410 (44%) | 437 (46%) | 416 (46%) | 0.252 |
| Smoker (current) | 79 (9%) | 84 (9%) | 93 (10%) | 112 (13%) | 0.003 |
| LDL cholesterol (mg/dl) | 128 ± 33 | 129 ± 33 | 127 ± 34 | 126 ± 33 | 0.124 |
| High-density lipoprotein cholesterol (mg/dl) | 53 ± 14 | 55 ± 15 | 55 ± 15 | 54 ± 14 | 0.077 |
| Diabetes mellitus | 148 (16%) | 135 (14%) | 111 (12%) | 117 (13%) | 0.039 |
| Subclinical cardiovascular diseases | 609 (66%) | 615 (67%) | 625 (68%) | 574 (65%) | 0.993 |
| C-Reactive protein (mg/L) | 2.03 (0.99–4.03) | 2.18 (1.12–5.03) | 2.54 (1.19–6.09) | 3.93 (1.65–8.56) | <0.001 |
| Cystatin C (mg/L) | 1.06 ± 0.26 | 1.07 ± 0.26 | 1.10 ± 0.28 | 1.10 ± 0.32 | <0.001 |
Values expressed as mean ± SD, number (percent), or median (interquartile range).