Table 2.

Multivariable model with myeloperoxidase (MPO) expressed in quartiles, including subjects with history of myocardial infarction (MI)

	HR (95% CI)	p Value	HR* (95% CI)	p Value
MPO quartiles (pmol/L)
<170	1.0 (reference)		1.0 (reference)
170–261	1.2 (0.94–1.52)	0.138	1.18 (0.92–1.50)	0.190
262–432	0.94 (0.73–1.21)	0.623	0.92 (0.71–1.18)	0.505
>432	1.34 (1.06–1.72)	0.013	1.22 (0.96–1.57)	0.108
MI	4.91 (4.08–5.91)	<0.01	4.73 (3.92–5.71)	<0.01
Age (yrs)	1.08 (1.07–1.10)	<0.01	1.08 (1.06–1.10)	<0.01
Men	1.16 (0.98–1.39)	0.09	1.21 (1.01–1.44)	0.034
Systolic blood pressure (mm Hg)†	1.26 (1.16–1.36)	<0.01	1.21 (1.12–1.31)	<0.01
Smoker (current)	1.50 (1.15–1.97)	<0.01	1.44 (1.10–1.90)	<0.01
LDL cholesterol (mg/dl)†	0.93 (0.85–1.01)	0.13	0.93 (0.85–1.02)	0.103
Diabetes mellitus	1.92 (1.56–2.36)	<0.01	1.86 (1.50–2.30)	<0.01
Subclinical cardiovascular diseases	1.93 (1.53–2.43)	<0.01	1.87 (1.48–2.36)	<0.01
C-Reactive protein†			1.13 (1.06–1.20)	<0.01
Cystatin C†			1.22 (1.15–1.29)	<0.01

^*When CRP and cystatin C were added to the multivariate model.

^†Per standard deviation increments (systolic blood presure = 21 mmHg, LDL cholesterol = 33 mg/dL, C-reactive protein = 9.4 mg/L, cystatin C = 0.28 mg/L).