Table 2.
Summary of the baseline characteristics for the average and high risk controls and cases.
| Characteristic | Healthy Controls (n=444) |
Benign Controls (n=124) |
Cases (n=143) |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Average Risk (n=150) |
High Risk (n=294) |
p-value* | Average Risk (n=110) |
High Risk (n=14) |
p-value* | Average Risk (n=102) |
High Risk (n=14) |
p-value* | |
| Age, median (range) | 52 (30–75) | 50 (31–83) | 0.09 | 54 (27–83) | 51 (25–71) | 0.14 | 58 (35–86) | 57 (19–80) | 0.83 |
| BMI, median (range) | 24.5 (18.5–42.0) | 24.2 (16.2–43.9) | 0.82 | 25.8 (18.8–51.6) | 26.6 (17.8–50.6) | 0.92 | 25.6 (19.2–42.9) | 24.5 (20.6–53.7) | 0.90 |
| RACE | |||||||||
| White | 128 (85.3) | 269 (91.5) | 95 (86.4) | 13 (92.9) | 84 (82.4) | 37 (90.3) | |||
| Asian | 3 (2.0) | 3 (1.0) | 4 (3.6) | 0 | 5 (4.9) | 1 (2.4) | |||
| Black | 0 | 0 | 1 (0.9) | 0 | 0 | 1 (2.4) | |||
| Other† | 0 | 6 (2.0) | 3 (2.7) | 0 | 4 (3.9) | 0 | |||
| Unknown | 19 (12.7) | 16 (5.5) | 0.01 | 7 (6.4) | 1 (7.1) | 0.90 | 9 (8.8) | 2 (4.9) | 0.26 |
| MENOPAUSE STATUS, n (%) | |||||||||
| Pre-menopause | 53 (35.3) | 96 (32.7) | 17 (15.5) | 3 (21.4) | 13 (12.7) | 2 (4.9) | |||
| Post-menopause | 97 (64.6) | 198 (67.3) | 0.57 | 93 (84.5) | 11 (78.6) | 0.57 | 89 (87.3) | 39 (95.1) | 0.17 |
| HRT Use (ever), n (%) | |||||||||
| No | 32 (21.3) | 178 (60.6) | 48 (43.6) | 6 (42.9) | 42 (41.2) | 14 (34.2) | |||
| Yes | 45 (30.0) | 110 (37.4) | 53 (48.2) | 8 (57.1) | 47 (46.1) | 24 (58.5) | |||
| Unknown | 73 (48.7) | 6 (2.0) | <0.001 | 9 (8.2) | 0 | 0.51 | 13 (12.7) | 3 (7.3) | 0.36 |
*
p-values were obtained by Wilcoxon rank-sum test for continuous variables and chi-square for catergorical variables.
†
Other race includes American/Alaskan Indians and women who reported more than one race.