Table 3.

Ictal SPECT decreases: localization and lateralization of seizure onset

Patienta	Overall Localizationb	ISAS Hypo- perfusion	L hemisphere hypoperfusion volumec	R hemisphere hypoperfusion volumec	Asymmetry Indexd	Side of greater hypoperfusion	Ipsi- or contra- lateral to localization
Pre-generalization
1	LH	LF	7367	1342	0.69	L	I
2	LH	RO	10 772	23 805	−0.38	R	C
3	RT NC	RP, O	2031	3530	−0.27	R	I
4	Unlocalized	RF, P	10 075	15 218	−0.20	R	NA
5	LT versus RT NC	LF	4690	1734	0.46	L	NA
6	LT	LP	2235	1940	0.07	L	I
7	LT	BiF	12 890	11 280	0.07	L	I
8	RH	RP	1348	4438	−0.53	R	I
9	LT	RF, P, T	4956	23 453	−0.65	R	C
10	RH	LT, P	7370	6358	0.07	L	C
11	Multifocal	BiO	20 647	17 345	0.09	L	NA
12	RT NC	RF, LO	17 519	10 538	0.25	L	C
Generalization
13	LRo (C3, P3)	BiP, O	4871	15 641	−0.53	R	C
14	LH	RP	1110	17 331	−0.88	R	C
15	RH	LF, O	14 753	674	0.91	L	C
16	L mesial T	BiF	18211	15 521	0.08	L	I
17	RH	LF	15 332	1850	0.78	L	C
18	LH	BiF	1560	2194	−0.17	R	C
19	Unlocalized	BiF,P	13741	15 584	−0.06	R	NA
20	LH multifocal	LF	10 136	10 726	−0.03	R	C
21	Unlocalized	RF, T	3489	6286	−0.29	R	NA
22	RH	BiF,P	26 728	22 833	0.08	L	C
23	RH	LF, T, P	21 020	4649	0.64	L	C
24	LH	RP, O	6594	14631	−0.38	R	C

a Patients listed in order of injection time from seizure onset (Pre-generalization group), or generalization (Generalization group), as in Table 1.

b See Supplementary Tables 1 and 2 online for details.

c Volume expressed as number of significant voxels; voxel dimensions 2 × 2 × 2 mm (see Methods section).

d (L−R)/(L+R) See Methods section.

R = right; L = left; T = temporal; P = parietal; F = frontal; O = occipital; Ro = Rolandic; H = hemisphere; Bi = bilateral; NC = neocortical; I = ipsilateral to overall localization; C = contralateral.