Table 3.

P-values of cross-sectional differences in cognitive performance between the CN subjects with the top 25% of the SPARE-AD scores and the remaining 75%

	Mean scores	Mean scores adjusted (for sex and age)	First visit scores	First visit scores adjusted	Last visit scores	Last visit scores adjusted
CVLT List A Sum	0.0075	0.5155	0.0020	0.1797	0.3357	0.3754
CVLT Long Delay Free	0.0067	0.3150	0.0067	0.2674	0.1817	0.8458
BVRT Errors	0.0930	0.9728	0.3505	0.8944	0.5994	0.5592
MMSE	0.1719	0.9666	0.0092	0.0174	0.5203	0.8606

Column labels indicate the scores used in the analysis, e.g. ‘mean scores’ indicates the P-value is based on mean cognitive performance and mean SPARE-AD index over time. Covariates in adjusted comparisons are baseline age and sex.