Table 3.
Correlation results from the validation cohort (ADNI subjects) between the automated MRI measures that best discriminated the MCI group and clinical, neuropsychological and CSF biomarker evaluations
| Region of interest | CDR-SB | MMSE | AVLT 5 min recall | AVLT 30 min recall | Trails B | Tau | P-Tau | Abeta 42 |
|---|---|---|---|---|---|---|---|---|
| Entorhinal cortex thickness | −0.81 (0.0001) | 0.72 (0.0001) | 0.66 (0.0001) | 0.70 (0.0001) | −0.51 (0.0001) | −0.41 (0.0001) | −0.47 (0.0001) | 0.38 (0.0001) |
| Hippocampal volume | −0.71 (0.0001) | 0.60 (0.0001) | 0.62 (0.0001) | 0.62 (0.0001) | −0.51 (0.0001) | −0.37 (0.0003) | −0.44 (0.0001) | 0.43 (0.0001) |
| Supramarginal gyrus thickness | −0.50 (0.0001) | 0.43 (0.0001) | 0.39 (0.0003) | 0.42 (0.0001) | −0.39 (0.0001) | −0.33 (0.0003) | −0.38 (0.0003) | 0.26 (0.006) |
Spearman's rank correlation coefficients listed with P-values in parenthesis.