Figure 5.

Age-related reduction in the volume of the ischaemic lesion in patients with acute ischaemic stroke and effect of thrombolysis. (A) Distribution of ages among the studied stroke population. (B) Proportion of patients having a lesion volume larger than 14cc at DWI performed at arrival regarding age decades. (C) Correlation between neurological scores (NIHSS) and infarct extension (DWI) both measured at stroke patient arrival at the emergency department. (D) MRI of two representative cases of human MCAO with ischaemic infarct observed at emergency department arrival (within 3 h of stroke onset). Both cases have similar location of the MCAO, however, upper case (36 years) has a measured DWI volume of 21cc as compared with bottom case (79 years) with DWI volume of 12cc at arrival.