Figure 14.
Two-compartment pharmocokinetic model representing the distribution of the contrast agent in plasma and injured spinal cord tissue. The subscripts p and sc denote plasma and spinal cord. [C]p(t) and [C]sc(t) are time-dependent concentrations in mmol/L in plasma and spinal cord compartments, respectively. The parameters kp-sc and ksc-p denote transfer rate constants in l/min for forward transfer of the contrast agent from plasma-to-spinal cord and reverse transfer from spinal cord-to-plasma compartments, respectively.