Table 1.
Clinical characteristics of neurotrophins and receptors in the synovial fluids of SpA, RA, and OA patients
| Patient Groups | Clinical characteristics | |||||||||
| age | gender | DD (y) | SJC | TJC | CRP (mg/l) | ESR (mm) | SFc/μl | %PMN | ||
| SpA (n = 16) | median | 37 | 6 f/10 m | 5 | 2* | 1* | 10.5* | 20 | 7025* | 72 |
| SD | 16.8 | 5.9 | 1.2 | 1.9 | 23 | 15 | 8825 | 26 | ||
| (range) | (16 to 65) | (0.3 to 18) | (1 to 4) | (0 to 8) | (1 to 99) | (3 to 54) | (2500 to 31100) | (5 to 92) | ||
| RA (n = 9) | median | 49 | 8 f/1 m | 5 | 5# | 3# | 11.7# | 26 | 7950# | 76 |
| SD | 15.3 | 9.2 | 3.2 | 1.8 | 29 | 8.8 | 3645 | 11 | ||
| (range) | (37 to 77) | (1 to 26) | (2 to 13) | (2 to 7) | (7.5 to -95) | (12 to 67) | (2600 to 1300) | (50 to 90) | ||
| OA (n = 7) | median | 67 | 5 f/2 m | 6 | 1 | 1 | 3 | 17 | 700 | 60 |
| SD | 5.8 | 5.7 | 0.5 | 0.4 | 1.1 | 5.6 | 1096 | 33 | ||
| (range) | (58 to 75) | (2 to 18) | (1 to 2) | (1 to 2) | (1.6 to 4.5) | (12 to 25) | (100 to 3250) | (5 to 90) | ||
Table 1 shows the clinical data and parameters of disease activity of 16 spondyloarthritis (SpA), 9 rheumatoid arthritis (RA), and 7 osteoarthritis (OA) patients used for the RT-PCR measurements on the synovial fluid samples. Swollen joint count (SJC), tender joint count (TJC), C-reactive protein (CRP), and synovial fluid (SF) leukocyte counts were higher in both SpA (*) and RA (#) as compared with OA; Mann Whitney U test; P < 0.05).
DD = disease duration given in years; ESR = erythrocyte sedimentation rate; f = female; m = male; PMN = percentage of polymorphonuclear cells of SF leukocytes; OA = osteoarthritis; RA = rheumatoid arthritis; SD = standard deviation; SpA = spondyloarthritis.