Table 3.

Chemokine receptor expression by CD19⁺ CD27⁺ memory B cells from peripheral blood of healthy donors and RA patients and in RA synovium

	Peripheral blood		Synovium
Chemokine receptor	Control (n = 13)	RA (n = 20)	(n = 10)
CXCR1	5.0 ± 0.6%	16.9 ± 1.2%a	39.0 ± 2.2%b
CXCR2	3.4 ± 0.4%	7.7 ± 0.6%a	31.2 ± 1.6%b
CXCR4	60.0 ± 0.9%	47.5 ± 2.3%a	92.1 ± 0.7%b
CCR2	2.8 ± 0.4%	7.6 ± 0.6%a	28.7 ± 1.8%b

^a indicates significant difference (P < 0.02) between controls and patients with rheumatoid arthritis (RA);

^b indicates significant difference (P < 0.00001) between RA blood and synovium.

Data are means ± standard error of the mean.