Table 2.
Summary of secondary endpoints: descriptive statistics
Bone marrow edema | Defects | Erosions | Synovitis | |
Patients with this finding at least once during the study, number (percentage) | 16 (34.8%) | 13 (28.3%) | 16 (34.8%) | 44 (73.9%) |
Joints with this finding at least once during the study, number (percentage) | 28 (10.1%) | 24 (8.7%) | 30 (10.9%) | 102 (37%) |
Number of times the finding was observed | 45 | 45 | 70 | 174 |
Percentage of time the finding was observed with bone marrow edema | - | 26.7% | 35.7% | 21.8% |
Percentage of time the finding was observed with defects | 26.7% | - | 20% | 14.4% |
Percentage of time the finding was observed with erosions | 60% | 31.1% | - | 33.9% |
Percentage of time the finding was observed with synovitis | 91.1% | 64.4% | 74.1% | - |
The 46 patients who completed more than one study are considered here. Two hundred seventy-six joints were imaged by magnetic resonance imaging (MRI) at least twice. A single joint was considered to have the finding if it appeared once in that joint during any of the MRI studies. The total number of times each characteristic was found was also counted, as was the percentage of the time each finding occurred with another. For examples of how these data were calculated, please refer to items (c) and (d) of the Descriptive data section of Materials and methods.