Table 7. Multivariate analysis of groups of diagnostic factors for the diagnosis of Haemophilus influenzae type b.

Diagnostic Factors	Haemophilus influenzae type b
	OR 95%CI	P	% PPV 95%CI	% NPV 95%CI
Absence of haemorrhagic rash	13.00 6.82–24.76	<0.001
Age≥1 year	1.84 1.16–2.74	0.010
Absence of headache	3.09 1.97–4.85	<0.001
CSF Glu<40 mg/dL	3.49 2.26–5.40	<0.001
Absence of haemorrhagic rash+Age≥1 year+Absence of headache+CSF Glu<40 mg/dL			54.4 41.9–66.5	83.0 80.8–85.0
Absence of heamorrhagic rash	13.61 6.93–26.72	<0.001
Age≥1 year	2.04 1.25–3.31	0.004
CSF Glu<40 mg/dL	3.62 2.32–5.66	<0.001
Absence of headache	3.01 1.89–4.80	<0.001
Peripheral WBC<15000/µL	1.74 1.15–2.63	<0.001
Absence of heamorrhagic rash+Age≥1 year+CSF Glu<40 mg/dL+Absence of headache+Peripheral WBC<15000/µL			58.5 42.1–73.7	82.0 80.1–84.3
Absence of haemorrhagic rash	11.09 6.01–20.46	<0.001
CSF Glu<40 mg/dL	3.09 2.03–4.69	<0.001
Absence of headache	2.27 1.55–3.32	<0.001
Haemorrhagic rash+CSF Glu<40 mg/dL+Absence of headache			44.4 37.2–51.8	85.3 83.1–87.3
	Non Haemophilus influenzae type b
Haemorrhagic rash	13.46 7.35–24.66	<0.001
Headache	2.38 1.65–3.43	<0.001
Haemorrhagic rash+Headache			97.9 95.2–99.3	22.7 20.2–25.3