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. 2009 Jul 29;4(7):e6426. doi: 10.1371/journal.pone.0006426

Table 10. Positive Predictive Values (PPV) of diagnostic factors for the diagnosis of causative pathogens.

Diagnostic Factors Diagnosed Organism
No. of Positive Samples/No. of Total Samples (% PPV)
N.meningitidis S. pneumoniae H. influenzae Other
Age<1 y 223/440 (50.7) 74/440 (16.8) 102/440 (23.2) 41/440 (9.3)
Fever≥38°C 404/652 (62.0) 93/652 (14.3) 133/652 (20.4) 22/652 (3.4)
Headache 366/496 (73.8) 65/496 (13.1) 87/496 (11.5) 8/496 (1.6)
Vomiting 435/678 (64.2) 90/678 (13.3) 137/678 (20.2) 16/678 (2.4)
Meningeal signs 525/824 (63.7) 118/824 (14.3) 167/824 (20.3) 14/824 (1.7)
Haemorrhagic rash 511/547 (93.4) 17/547 (3.1) 17/547 (3.1) 2/547 (0.4)
Seizures 85/201 (42.3) 65/201 (32.3) 39/201 (19.4) 12/201 (6.0)
Positive gram stain 451/784 (57.5) 140/784 (17.9) 173/784 (22.1) 20/784 (2.6)