Table 1. The histopathological findings and length of time from initial assessment of 29 patients who were diagnosed with breast cancer having been previously discharged from the breast clinic.
| Histopathology of interval cancer | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Interval between initial assessment and interval cancer (months) | No. of patients | Mean age years (range) | Mammographic density (BI-RADS 1–4) | Mean size mm (range) | Grade | Nodal statusa | ER status | % of patients with NPI >3.4 (moderate/poor/very poor prognostic groups)b | Interval cancer rate per 1000 patients discharged from a symptomatic clinic |
| 0–12c | 6 | 49 (39–56) | 1: 0 2: 0 3: 3 4: 3 | 29 (8–52) | Gd 1: 0 Gd 2: 2 Gd 3: 3 | 1: 2 2: 1 3: 2 | +ve 4 −ve 1 | 60 | 0.9 |
| 13–24 | 12 | 57 (41–96) | 1: 2 2: 1 3: 3 4: 6 | 29 (9–60) | Gd 1: 1 Gd 2: 4 Gd 3: 7 | 1: 4 2: 4 3: 4 | +ve 6 −ve 6 | 91 | 1.7 |
| 25–36 | 11 | 56 (38–87) | 1: 0 2: 0 3: 10 4: 1 | 25 (18–40) | Gd 1: 1 Gd 2: 2 Gd 3: 8 | 1: 5 2: 4 3: 2 | +ve 8 −ve 3 | 91 | 1.6 |
| Totalc | 29 | 55 (38–96) | 1: 2 2: 1 3: 16 4: 10 | 27 (8–60) | Gd 1: 2 Gd 2: 8 Gd 3: 18 | 1: 11 2: 9 3: 8 | +ve 18 −ve 10 | 86 | 4.1 |
a
According to the Nottingham Prognostic Index (Blamey et al, 2007a, 2007b).
b
NPI indicates Nottingham Prognostic Index (Blamey et al, 2007a, 2007b).
c
Final histology unknown in one patient who emigrated and underwent treatment abroad.