Table 1. Distribution of ApoE genotypes by cases and controls.
| Variable | All cases N (%) | Controls N (%) | P-value | OR (95% CI) all cases vs controls | ||
|---|---|---|---|---|---|---|
| ApoE4 | ||||||
| TT | 568 (75.0) | 634 (73.4) | 0.56 | 1.00 (Referent) | ||
| CT | 172 (22.7) | 204 (23.6) | 0.94 (0.75, 1.19) | |||
| CC | 17 (2.2) | 26 (3.0) | 0.73 (0.39, 1.36) | |||
| ApoE2 | ||||||
| TT | 673 (86.4) | 779 (85.5) | 0.69 | 1.00 (Referent) | ||
| CT | 103 (13.2) | 126 (13.8) | 0.95 (0.72, 1.25) | |||
| CC | 3 (0.4) | 6 (0.7) | 0.58 (0.14, 2.32) | |||
| MSS/L N (%) | MSI-H N (%) | OR (95% CI) MSS/L vs controls | OR (95% CI) MSI-H vs controls | |||
| ApoE4 | ||||||
| TT | 391 (75.0) | 63 (73.3) | 634 (73.4) | 0.85 | 1.00 (Referent) | 1.00 (Referent) |
| CT | 119 (22.8) | 20 (23.3) | 204 (23.6) | 0.95 (0.73, 1.23) | 0.99 (0.58, 1.67) | |
| CC | 11 (2.1) | 3 (3.5) | 26 (3.0) | 0.69 (0.34, 1.40) | 1.16 (0.34, 3.94) | |
| ApoE2 | ||||||
| TT | 541 (86.8) | 94 (84.7) | 779 (85.5) | 0.70 | 1.00 (Referent) | 1.00 (Referent) |
| CT/CC | 82 (13.2) | 17 (15.3) | 132 (14.5) | 0.89 (0.66, 1.20) | 1.07 (0.62, 1.85) | |
ApoE2 represents ApoE protein with 112Cys/158Cys residues, ApoE4 represents ApoE protein with 112Arg/158Arg residues, MSI-H=high frequency microsatellite instability, MSS/L=microsatellite stable/low-frequency microsatellite instability, homozygous wild-type allele carriers were considered as the referent groups.