Table 2. Association of sex, age at diagnosis, red meat intake (servings per week), total fat intake (grams), saturated fat intake (grams), cholesterol intake (milligrams), dietary folacin (milligrams) and alcohol intake (drinks/week) between CRC cases and controls.
| Variable | Case N (%) | Control N (%) | Total N (%) | P-value | OR (95% CI) |
|---|---|---|---|---|---|
| Sex | |||||
| Female | 441 (48.7) | 402 (46.2) | 843 (47.5) | 0.30 | 1.00 |
| Male | 465 (51.3) | 468 (53.8) | 933 (52.5) | 0.91 (0.75, 1.09) | |
| Age at diagnosis | |||||
| <50 | 113 (12.5) | 77 (8.9) | 190 (10.7) | 0.01 | 1.00 (Referent) |
| 50–59 | 257 (28.4) | 299 (34.4) | 556 (31.3) | 0.59 (0.42, 0.82) | |
| 60–69 | 402 (44.4) | 372 (42.8) | 774 (43.6) | 0.74 (0.53, 1.02) | |
| 70+ | 133 (14.7) | 121 (13.9) | 254 (14.3) | 0.75 (0.51, 1.10) | |
| Red meat consumption/week | |||||
| 0.0–2.0 | 247 (27.9) | 317 (36.8) | 564 (32.3) | <0.001 | 1.00 (Referent) |
| 2.1–3.0 | 186 (21.0) | 159 (18.5) | 345 (19.7) | 1.50 (1.15, 1.97) | |
| 3.1–5.0 | 225 (25.4) | 205 (23.8) | 430 (24.6) | 1.41 (1.09, 1.81) | |
| >5.0 | 228 (25.7) | 180 (20.9) | 408 (23.4) | 1.63 (1.26, 2.10) | |
| Total fat intake (grams) | |||||
| 0–50 | 175 (19.3) | 222 (25.5) | 397 (22.4) | <0.001 | 1.00 (Referent) |
| >50–70 | 262 (28.9) | 244 (28.0) | 506 (28.5) | 1.36 (1.05, 1.77) | |
| >70–90 | 197 (21.7) | 205 (23.6) | 402 (22.6) | 1.22 (0.92, 1.61) | |
| >90 | 272 (30.0) | 199 (22.9) | 471 (26.5) | 1.73 (1.32, 2.27) | |
| Saturated fat intake (grams) | |||||
| 0–15 | 200 (22.1) | 254 (29.2) | 454 (25.6) | <0.01 | 1.00 (Referent) |
| >15–20 | 206 (22.7) | 204 (23.4) | 410 (23.1) | 1.28 (0.98, 1.68) | |
| >20–27 | 234 (25.8) | 203 (23.3) | 437 (24.6) | 1.46 (1.12, 1.91) | |
| >27 | 266 (29.4) | 209 (24.0) | 475 (26.7) | 1.62 (1.25, 2.09) | |
| Dietary cholesterol (milligrams) | |||||
| 0–150 | 169 (18.7) | 216 (24.8) | 385 (21.7) | <0.01 | 1.00 (Referent) |
| >150–220 | 265 (29.2) | 262 (30.1) | 527 (29.7) | 1.29 (0.99, 1.68) | |
| >220–290 | 222 (24.5) | 202 (23.2) | 424 (23.9) | 1.40 (1.06, 1.85) | |
| >290 | 250 (27.6) | 190 (21.8) | 440 (24.8) | 1.68 (1.28, 2.22) | |
| Dietary folacin (miligrams) | |||||
| 0–250 | 201 (22.2) | 214 (24.6) | 415 (23.4) | 0.14 | 1.00 (Referent) |
| >250–370 | 264 (29.1) | 225 (25.9) | 489 (27.5) | 1.25 (0.96, 1.62) | |
| >370–520 | 232 (25.6) | 203 (23.3) | 435 (24.5) | 1.22 (0.93, 1.59) | |
| >520 | 209 (23.1) | 228 (26.2) | 437 (24.6) | 0.98 (0.75, 1.28) | |
| Alcoholic drinks/week | |||||
| None | 224 (25.9) | 194 (23.2) | 418 (24.6) | 0.40 | 1.00 (Referent) |
| 0.1–2.0 | 196 (22.6) | 208 (24.9) | 404 (23.7) | 0.82 (0.62, 1.07) | |
| 2.1–7.0 | 228 (26.3) | 236 (28.2) | 464 (27.3) | 0.84 (0.64, 1.09) | |
| >7.0 | 218 (25.2) | 198 (23.7) | 416 (24.4) | 0.95 (0.73, 1.25) | |
CI=confidence interval; OR=odds ratios adjusted for age and sex. All samples with unavailable data have been omitted from the analyses. Female participants, participants with age <50 along with lowest dietary groups have been used as the referent goups.