Table 1. Clinicopathlogial significance of ID1 mRNA expression in gastric cancer patients.
Bone marrow | Peripheral blood | |||||
---|---|---|---|---|---|---|
Features | Number | ID1 mRNA expression (mean±s.d.) | P-value | Number | ID1 mRNA expression (mean±s.d.) | P-value |
Age | 289 | 62.3±11.9 | — | 196 | 62.9±12.2 | — |
Sex (M : F) | 289 | 190 : 99 | — | 196 | 131 : 65 | — |
Tumour size | 0.01 | 0.002 | ||||
⩽5 cm | 126 | 311±146 | 85 | 24.8±12.2 | ||
⩾5 cm | 160 | 795±129 | 110 | 64.6±10.7 | ||
Depth of tumour invasion a | 0.01 | 0.004 | ||||
m, sm | 90 | 210±171 | 62 | 12.9±14.2 | ||
mp, ss, se, si | 199 | 744±115 | 134 | 62.8±9.6 | ||
Venous invasion | 0.97 | 0.007 | ||||
Positive | 72 | 580±199 | 50 | 77.8±15.2 | ||
Negative | 188 | 571±123 | 128 | 28.9±9.5 | ||
Lymphatic invasion | 0.001 | 0.02 | ||||
Positive | 156 | 850±132 | 110 | 57.8±10.3 | ||
Negative | 104 | 158±162 | 68 | 18.2±13.1 | ||
Lymph node metastasis | 0.001 | 0.02 | ||||
Positive | 188 | 800±121 | 132 | 56.7±9.6 | ||
Negative | 79 | 58.7±186 | 50 | 12.4±15.6 | ||
Peritoneal dissemination b | 0.002 | <0.0001 | ||||
Positive | 70 | 1102±194 | 40 | 119±17.1 | ||
Negative | 218 | 412±110 | 156 | 28.6±8.6 |
Tumour invasion of mucosa (m), submucosa (sm), muscularis propria (mp), subserosa (ss), penetration of serosa (se) and invasion of adjacent strucures (si).
Peritoneal dissemination: peritoneal cytology or metastasis positive.