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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Genes Immun. 2009 Apr 23;10(5):539–545. doi: 10.1038/gene.2009.30

Table 4.

Sample size required for p = 10−5, power = 80%, affected only and case-control design (1:1).

Locus specific ancestry risk Affected Only Case-Control
Admixture Proportion Admixture Proportion
10% 20% 30% 40% 50% 10% 20% 30% 40% 50%
1.25 11638 9806 7471 6537 6276 46551 39223 29884 26149 25103
1.5 3525 1983 1511 1322 1269 14099 7931 6042 5287 5076
1.75 1850 1041 793 694 666 7401 4163 3172 2776 2665
2 1206 678 517 452 434 4824 2714 2068 1809 1737