Table 1.
Results of univariate analysis in ischaemic stroke patients with anterior cerebral artery (ACA) infarction compared with middle cerebral artery (MCA) and posterior cerebral artery (PCA)
| Data | Anterior cerebral artery | Middle cerebral artery | ACA vs MCA P value* |
Posterior cerebral artery | ACA vs PCA P value† |
| Total patients | 51 | 1355 | 232 | ||
| Males | 27 (52.9) | 635 (46.9) | 0.238 | 128 (55.2) | 0.445 |
| Age, years, mean (SD) | 74.4 (14.7) | 76 (11.4) | 0.331 | 73.9 (11.9) | 0.801 |
| Age ≥ 85 years | 11 (21.6) | 302 (22.3) | 0.904 | 37 (15.9) | 0.219 |
| Cerebrovascular risk factors | |||||
| Hypertension | 28 (54.9) | 769 (56.8) | 0.886 | 136 (58.6) | 0.369 |
| Diabetes mellitus | 15 (29.4) | 301 (22.2) | 0.150 | 70 (30.2) | 0.530 |
| Valve heart disease | 1 (2) | 95 (7) | 0.124 | 16 (6.9) | 0.153 |
| Ischaemic heart disease | 4 (7.8) | 223 (16.5) | 0.066 | 36 (15.5) | 0.111 |
| Atrial fibrillation | 12 (23.5) | 461 (34) | 0.077 | 62 (26.7) | 0.391 |
| Congestive heart dailure | 4 (7.8) | 88 (6.5) | 0.431 | 9 (3.9) | 0.190 |
| TIA | 4 (7.8) | 152 (11.2) | 0.314 | 30 (12.9) | 0.225 |
| Previous cerebral infarction | 10 (19.6) | 225 (16.6) | 0.342 | 41 (17.7) | 0.440 |
| Previous cerebral haemorrhage | 1 (2) | 10 (0.7) | 0.335 | 4 (1.7) | 0.633 |
| Periphery arterial disease | 2 (3.9) | 100 (7.4) | 0.269 | 13 (5.6) | 0.472 |
| Obesity | 4 (7.8) | 51 (3.8) | 0.135 | 11 (4.7) | 0.276 |
| Alcohol abuse (> 80 g/day) | 0 | 39 (2.9) | 0.232 | 1 (0.4) | 0.820 |
| Smoking (> 20 cigarettes/day) | 3 (5.9) | 132 (9.7) | 0.261 | 20 (8.6) | 0.376 |
| Dyslipemia | 9 (17.6) | 226 (16.7) | 0.458 | 45 (19.4) | 0.474 |
| Clinical features | |||||
| Sudden onset | 27 (52.9) | 722 (53.3) | 0.537 | 108 (46.6) | 0.251 |
| Headache | 0 | 120 (8.9) | 0.010 | 53 (22.8) | 0.000 |
| Dizziness symptoms | 2 (3.9) | 14 (1) | 0.112 | 7 (3) | 0.504 |
| Seizures | 1 (2) | 24 (1.8) | 0.606 | 0 | 0.180 |
| Nausea, vomiting | 2 (3.9) | 62 (4.6) | 0.587 | 17 (7.3) | 0.299 |
| Speech disturbances | 22 (43.1) | 816 (60.2) | 0.011 | 70 (30.2) | 0.054 |
| Altered consciousness | 4 (7.8) | 278 (20.5) | 0.014 | 28 (12.1) | 0.277 |
| Motor deficit‡ | 44 (86.3) | 1145 (84.5) | 0.459 | 90 (38.8) | 0.000 |
| Sensory | 15 (29.4) | 554 (40.9) | 0.066 | 119 (51.3) | 0.003 |
| Aetiological stroke subtypes | 0.337 | 0.001 | |||
| Atherothrombotic | 15 (29.4) | 395 (29.2) | 68 (29.3) | ||
| Lacunar | 6 (11.8) | 301 (22.2) | 80 (34.5) | ||
| Cardioembolic | 23 (45.1) | 482 (35.6) | 50 (21.6) | ||
| Unknown aetiology | 6 (11.8) | 124 (9.2) | 20 (8.6) | ||
| Unusual cause | 1 (2) | 52 (3.9) | 14 (6) | ||
| Symptom-free at discharge | 5 (9.8) | 149 (11) | 0.507 | 45 (19.4) | 0.072 |
| Cardiac events | 2 (3.9) | 78 (5.8) | 0.436 | 6 (2.6) | 0.439 |
| Infectious events | 6 (11.8) | 237 (17.5) | 0.194 | 15 (6.5) | 0.155 |
| Respiratory events | 4 (7.8) | 176 (13) | 0.196 | 12 (5.2) | 0.321 |
| Length of hospital stay, median (25th–75th percentile) | 12 (10–24) | 13 (9–23) | 0.895 | 12.8 (8–22) | 0.601 |
| In-hospital deaths | 4 (7.8) | 235 (17.3) | 0.048 | 9 (3.9) | 0.190 |
Data are n (%) unless otherwise stated.
*P = 0.337; †P = 0.001.
†Association with motor hemonegligence in 11.8%; concomitant presence of grasping in 17.6%; callosal disconnection syndrome in 5.9%.