Table 1.
Demographic and clinical characteristics according to GOLD stages
| GOLD II (n = 33) | GOLD III (n = 37) | GOLD IV (n = 18) | |
|---|---|---|---|
| Agens | 58.5 (10.4) | 58.6 (10.4) | 57.0 (8.5) |
| Pack-years of smokingns | 32.4 (19.4) | 41.1 (31.9) | 45.8 (26.4) |
| Duration of diseasens | 5.8 (4.4) | 7.0 (6.0) | 10.5.2 (8.9) |
| PaO2 (mm Hg)*** | 81.4 (7.0) | 76.4 (9.8) | 64.3 (9.3)+++@@ |
| PaCO2 (mm Hg)** | 40.2 (2.3) | 43.7 (5.7) | 47.0 (5.1)++ |
| 6-min walk | 374.3 (128.6) | 300.5 (120.5)+ | 235.9 (81.5)+++ |
| distance (m)*** | |||
| MMRC grade** | |||
| Grade II | 16 (69.6) | 4 (17.4) | 3 (13) |
| Grade III | 14 (33.3) | 18 (42.9) | 10 (23.8) |
| Grade IV | 3 (13) | 15 (65.2) | 5 (21.7) |
| OCD score (mm)** | 55.5 (16.6) | 41.9 (15.6)++ | 44.0 (16.6) |
| BDI score*** | 6.9 (2.7) | 4.5 (2.5)++ | 5.3 (2.2) |
| Post-BD FVC% predicted*** | 95.8 (13.1) | 79.6 (12.0)+++ | 67.8 (14.6)+++@@ |
| Post-BD FEV% predicted*** | 59.7 (7.2) | 39.4 (5.4)+++ | 26.3 (5.2)+++@@@ |
All data represent mean (SD) except the MMRC grades that show frequency (row percentages). ANOVA results (column 1):
***
: P <.001,
**
: P <.01, ns = not significant, P >.05; Post-hoc Bonferroni's test: vs column 2:
+++
: P <.001,
++
: P <.01; vs column 3:
@@@
: P <.001,
@@
: P <.01