Table 3.

Brain areas and their location (Talairach coordinates, x,y,z) where changes in Bmax/Kd (ΔD2R) in caudate and in putamen were correlated with BOLD changes (ΔBOLD) and significant differences in activation responses to VA task between SD and RW (ΔBOLD Main Effect)

Region	BA	x	y	z	Correlation Putamen DD2R vs. DBOLD	p	Correlation Caudate DD2R vs. DBOLD	p	ΔBOLD Main Effect (SD–RW)
Positive correlations
Middle R occipital	18	9	−69	3	r=0.61	p=0.02	r=0.65	p=0.01	NS
Middle R occipital	18	12	−81	12		NS	r=0.65	p=0.01	Z=2.2§
Lower R occipital	18	12	−75	−9		NS	r=0.67 p=0.009	p=0.009	Z=−1.8‡
Vermis		−3	−60	−24	r=0.70	p=0.006	r=0.64	p=0.02	NS
L cerebellum		−27	−69	−14	r=0.64	p=0.02	r=0.53	p=0.05	Z=−1.9‡
R cerebellum		6	−66	−33	r=0.77	p=0.002	r=0.72	p=0.004	NS
Negative correlations
Cingulate gyrus	32	0	36	−3	r=−0.72	p=0.004	r=−0.66	p=0.01	NS
R cingulate	24	9	33	−3	r=−0.84	p=0.0002	r=−0.79	p=0.0008	NS
R anterior insula	13	33	12	6	r=−0.67	p=0.009	r=−0.66	p=0.01	NS
L posterior insula	13	−33	−9	−6	r=−0.72	p=0.004	r=−0.82	p=0.0003	NS

For the correlations the “r” values along with their significance (p) are shown and for the BOLD “Main Effect” we show the Z values on those regions that showed significant differences between RW and SD at p<0.05 corrected for multiple comparisons and for cluster size of 27 voxels. Abbreviations correspond to BA = Brodman Area, L = left, R = right, SG = superior gyrus.

^§p_corr<0.005

^‡p_corr<0.05.