Table 1.
Comparisons of oxidants and antioxidants in HIV-1 infected patients.
Controls (MEAN ± S.D) N = 50 | HIV-1 Asymptomatic patients (MEAN ± S.D) N = 28 | HIV-1 Symptomatic patients (MEAN ± S.D) N = 22 | p value | |
MDA (n mol/mL) | 0.9 ± 0.2 | 2.2 ± 0.7 | 2.8 ± 0.8 | P < 0.01 |
TAC (μmol/L) | 1018.7 ± 125.6 | 754.6 ± 135.6 | 676.6 ± 154.1 | P < 0.01 |
Vitamin E (mg/L) | 10.0 ± 0.8 | 8.2 ± 0.6 | 7.4 ± 0.6 | P < 0.01 |
Vitamin C (mg/dl) | 6.3 ± 0.2 | 5.8 ± 0.2 | 3.6 ± 0.2 | P < 0.01 |
SOD activity (units/ml) | 8.75 ± 1.1 | 4.9 ± 0.4 | 3.7 ± 0.4 | P < 0.01 |
MDA – Malondialdehyde, TAC – Total Antioxidant Capacity, SOD – Superoxide Dismutase.