Fig 2 Odds ratios (95% confidence intervals) for all cause mortality, major coronary events, major cerebrovascular events, and incidence of cancer. (Mortality risk based on mean follow-up of 4.1 years, with data from nine trials, and 67 476 patients free of cardiovascular disease (no data available from HPS diabetic arm^w5). Risk of coronary events based on mean follow-up of 4.9 years, with data from eight trials, and 50 681 patients free of cardiovascular disease (no data available from ASPEN^w3 and JUPITER^w1). Risk of cerebrovascular events based on mean follow-up of 4.1 years, with data from nine trials, and 67 476 patients free of cardiovascular disease (no data available from HPS diabetic arm). Risk of cancer based on mean follow-up of 3.9 years, with data from six trials, and 52 027 patients free of cardiovascular disease (no data available from HPS, ASCOT,^w10 PROSPER,^w6 and ASPEN). See footnote to table 1 for full titles of studies. *Measures of heterogeneity