Table 1.

Effect of STZ, 1 wk of daily restraint stress, and 3 wks of oral Cort treatment on rat final body weights (BW) (% of initial BW) and adrenal, spleen, and thymus weights (mg/100 g BW)

Treatment	Adrenals	Spleen	Thymus	% Initial BW
Cont	16.75  ± 1.16	245.31  ± 10.51	175.78  ± 17.95	132.99  ± 2.12
Cont + R	15.23  ± 1.50	249.63  ± 15.30	180.25  ± 16.70	104.23  ± 0.06‡
STZ	21.53  ± 1.45*	161.80  ± 15.47†	39.75  ± 13.22‡	98.51  ± 3.18‡
STZ + R	27.36  ± 0.95‡	110.79  ± 11.96‡	26.23  ± 5.24‡	92.73  ± 1.54‡§
Cort, 400 μg/ml	5.6  ± 0.30‡	116.50  ± 7.40‡	58.70  ± 7.60‡	117.44  ± 5.91¶

*,  

^†, and  

^‡, P < 0.05, 0.01, and 0.001, respectively, compared with controls (Cont);  

^§, P < 0.005, compared with restraint-stressed group (Cont + R). No significant changes were detected in organ weights from controls left undisturbed for 1 wk and controls receiving 2.4% ethanol for 3 wks (the percent initial BW for the latter group was 172.47 ± 3.62 g.  

^¶, P < 0.01, compared with the latter control group). One-way ANOVA Tukey post hoc test. BW, body weight; R, restraint stress.